Blood transcriptomic discrimination of bacterial and viral infections in the emergency department: a multi-cohort observational validation study

By Josephine Galatioto | July 21, 2020

Abstract Background There is an urgent need to develop biomarkers that stratify risk of bacterial infection in order to support antimicrobial stewardship in emergency hospital admissions. Methods We used computational machine learning to derive a rule-out blood transcriptomic signature of bacterial infection (SeptiCyte™ TRIAGE) from eight published case-control studies. We then validated this signature by…

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