Diagnostics: Ruling In and Ruling Out Sepsis Using Likelihood Ratios of a Host Response Assay

From the Diagnostics publication on MDPI

Overview: SeptiCyte RAPID is an FDA-cleared gene expression test that quantifies host immune response to aid in the diagnosis of sepsis. The test yields a score (the SeptiScore) ranging from 0–15, distributed across four bands (1–4) based on increased likelihood of sepsis. Each band can be characterized by average positive and negative likelihood ratios (LR+ and LR−, respectively) for the discrimination of sepsis versus the non-infectious systemic inflammatory response syndrome (SIRS).

Source: Diagnostics on MDPI